Five Ibrutinib-Associated Side Effects That All Clinicians Should Be Aware of

Type B Wellens’ syndrome: Electrocardiogram patterns that clinicians should be aware of

In clinical practice, stress testing might be performed due to lack of typical ST segment elevation in Wellens’ syndrome to obtain more evidence of cardiac ischemia. However, increasing cardiac demand during stress testing may result in acute myocardial infraction, and even fatal dysrhythmia and death [5]. Therefore, it is essential to consider the coronary angiogram as the initial diagnostic m...

Staphylococcus lugdunensis; a pathogen that should be considered in Iran

Background: Staphylococcus lugdunensis is Gram-positive cocci of the staphylococcaceae family. S. lugdunensis despite having a clotting factor (wall coagulase), was classified in the coagulase negative staphylococcus group (CoNS) for lack of free coagulase. Although this bacterium is part of the human normal flora, in terms of virulence, S. lugdunensis is in second place after S. aureus. S. lug...

Whether all patients with Central precocious puberty should be treated?

Extended Abstract   Precocious puberty is the appearance of secondary sexual characteristics before 8 years old in girls and 9 years old in boys. Precocious puberty is divided into 3 groups of central, peripheral and normal variants. Central precocious puberty is accompanied by activation of hypothalamic-pituitary-gonadal axis which causes increase in secretion of GnRH, and in turn increase i...

Ocular side effects of biological agents in oncology: what should the clinician be aware of?

During the last 20 years, biologicals have become increasingly relevant in oncologic therapy. Depending on the medication used, there are different profiles of ocular side effects. Although these can be present in up to 70% of patients, they are generally underreported in the literature. Therefore, the pathophysiological details of their development are often poorly understood. Herein we attemp...

Anti-GAD positive stiff-person syndrome and cerebellar ataxia: two treatable conditions that clinicians should be aware of.